官方網(wǎng)站:http://jbx.sagepub.com/
投稿網(wǎng)址:https://us.sagepub.com/en-us/nam/journal-of-biomolecular-screening/journal201648
Advancing Life Sciences R&D: SLAS Discovery reports how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease.SLAS Discovery is a peer-reviewed journal that publishes scientific reports that enable and improve target validation, evaluate current drug discovery technologies, provide novel research tools, and incorporate research approaches that enhance depth of knowledge and drug discovery success.SLAS Discovery emphasizes scientific and technical advances in target identification/validation (including chemical probes, RNA silencing, gene editing technologies); biomarker discovery; assay development; virtual, medium- or high-throughput screening (biochemical and biological, biophysical, phenotypic, toxicological, ADME); lead generation/optimization; chemical biology; and informatics (data analysis, image analysis, statistics, bio- and chemo-informatics). Review articles on target biology, new paradigms in drug discovery and advances in drug discovery technologies.SLAS Discovery is of particular interest to those involved in analytical chemistry, applied microbiology, automation, biochemistry, bioengineering, biomedical optics, biotechnology, bioinformatics, cell biology, DNA science and technology, genetics, information technology, medicinal chemistry, molecular biology, natural products chemistry, organic chemistry, pharmacology, spectroscopy, and toxicology.SLAS Discovery is a member of the Committee on Publication Ethics (COPE) and was published previously (1996-2016) as the Journal of Biomolecular Screening (JBS).
推進(jìn)生命科學(xué)研發(fā):SLAS發(fā)現(xiàn)報(bào)告了科學(xué)家如何開(kāi)發(fā)和利用新技術(shù)和/或方法來(lái)提供和描述理解和治療人類疾病的化學(xué)和生物工具。SLAS Discovery是一個(gè)同行評(píng)審的期刊,它發(fā)布科學(xué)報(bào)告,以實(shí)現(xiàn)和改進(jìn)目標(biāo)驗(yàn)證,評(píng)估當(dāng)前的藥物發(fā)現(xiàn)技術(shù),提供新穎的研究工具,并結(jié)合研究方法,提高知識(shí)深度和藥物發(fā)現(xiàn)的成功率。SLAS發(fā)現(xiàn)強(qiáng)調(diào)了目標(biāo)識(shí)別/驗(yàn)證(包括化學(xué)探針、RNA沉默、基因編輯技術(shù))的科學(xué)和技術(shù)進(jìn)步;生物標(biāo)志物發(fā)現(xiàn);分析開(kāi)發(fā);虛擬、中或高通量篩選(生化和生物、生物物理、表型、毒理學(xué)、ADME);鉛生成/光學(xué)數(shù)字化;化學(xué)生物學(xué);信息學(xué)(數(shù)據(jù)分析、圖像分析、統(tǒng)計(jì)學(xué)、生物和化學(xué)信息學(xué))。綜述目標(biāo)生物學(xué)、藥物發(fā)現(xiàn)的新范式和藥物發(fā)現(xiàn)技術(shù)的進(jìn)展。SLAS的發(fā)現(xiàn)對(duì)分析化學(xué)、應(yīng)用微生物學(xué)、自動(dòng)化、生物化學(xué)、生物工程、生物醫(yī)學(xué)光學(xué)、生物技術(shù)、生物信息學(xué)、細(xì)胞生物學(xué)、DNA科學(xué)與技術(shù)、遺傳學(xué)、信息技術(shù)、醫(yī)學(xué)化學(xué)、分子生物學(xué)、天然產(chǎn)物化學(xué)、有機(jī)物等領(lǐng)域的研究者特別感興趣。化學(xué)、藥理學(xué)、光譜學(xué)和毒理學(xué)。SLAS Discovery是出版?zhèn)惱砦瘑T會(huì)(COPE)的成員,之前(1996-2016年)作為生物分子篩選雜志(JBS)出版。
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