Metallomics publishes cutting-edge investigations aimed at elucidating the identification, distribution, dynamics, role and impact of metals and metalloids in biological systems. Studies that address the “what, where, when, how and why” of these inorganic elements in cells, tissues, organisms, and various environmental niches are welcome, especially those employing multidisciplinary approaches drawn from the analytical, bioinorganic, medicinal, environmental, biophysical, cell biology, plant biology and chemical biology communities. We are particularly interested in articles that enhance our chemical and/or physical understanding of the molecular mechanisms of metal-dependent life processes, and those that probe the common space between metallomics and other ‘omics approaches to uncover new insights into biological processes.As we celebrate our 10-year anniversary in 2019, Metallomics seeks to position itself at the forefront of those advances in analytical chemistry destined to clarify the enormous complexity of biological systems. As such, we particularly welcome those papers that outline cutting-edge analytical technologies, e.g., in the development and application of powerful new imaging, spectroscopic and mass spectrometric modalities. Work that describes new insights into metal speciation, trafficking and dynamics in complex systems or as a function of microenvironment are also strongly encouraged. Studies that examine the interconnectivity of metal-dependent processes with systems level responses relevant to organismal health or disease are also strongly encouraged, for example those that probe the effect of chemical exposure on metal homeostasis or the impact of metal-based drugs on cellular processes.Authors are asked to use the Statement on the “Significance to Metallomics”, required upon submission of all manuscripts, as a mechanism to highlight these interdisciplinary advances of significance to the metals in biology and metallomics communities.

金屬組學(xué)發(fā)表前沿研究，旨在闡明金屬和金屬化合物在生物系統(tǒng)中的識別、分布、動力學(xué)、作用和影響。針對細(xì)胞、組織、有機(jī)體和各種環(huán)境生態(tài)位中這些無機(jī)元素的“什么、在哪里、何時、如何和為什么”的研究是受歡迎的，特別是那些采用來自分析、生物無機(jī)、醫(yī)學(xué)、環(huán)境、生物物理、細(xì)胞生物學(xué)、植物生物學(xué)和化學(xué)生物學(xué)社區(qū)的多學(xué)科方法的研究。我們特別感興趣的是那些增強(qiáng)我們對金屬依賴生命過程的分子機(jī)制的化學(xué)和/或物理理解的文章，以及那些探索金屬組學(xué)和其他組學(xué)方法之間的共同空間的文章，以揭示對生物過程的新見解。在2019年我們慶祝成立10周年之際，金屬組學(xué)試圖將自己定位于分析化學(xué)前沿，這些進(jìn)展注定會闡明生物系統(tǒng)的巨大復(fù)雜性。因此，我們特別歡迎那些概述尖端分析技術(shù)的論文，例如在發(fā)展和應(yīng)用強(qiáng)大的新成像、光譜和質(zhì)譜方法方面。還強(qiáng)烈鼓勵對復(fù)雜系統(tǒng)或作為微環(huán)境功能的金屬形態(tài)、販運(yùn)和動力學(xué)的新見解的工作。研究金屬依賴過程與機(jī)體健康或疾病相關(guān)的系統(tǒng)級反應(yīng)之間的相互聯(lián)系也受到強(qiáng)烈鼓勵，例如，研究化學(xué)暴露對金屬穩(wěn)態(tài)的影響或金屬藥物對細(xì)胞過程的影響。作者被要求使用“對金屬組學(xué)的意義”的聲明，在提交所有手稿時要求，作為一種機(jī)制，以突出這些跨學(xué)科的進(jìn)展，在生物學(xué)和金屬組學(xué)社區(qū)的意義。