MISSION STATEMENTThe mission of MCP is to foster the development and applications of proteomics in both basic and translational research. MCP will publish manuscripts that report significant new biological or clinical discoveries underpinned by proteomic observations across all kingdoms of life. Manuscripts must define the biological roles played by the proteins investigated or their mechanisms of action.The journal also emphasizes articles that describe innovative new computational methods and technological advancements that will enable future discoveries. Manuscripts describing such approaches do not have to include a solution to a biological problem, but must demonstrate that the technology works as described, is reproducible and is appropriate to uncover yet unknown protein/proteome function or properties using relevant model systems or publicly available data.SCOPE OF THE JOURNALFundamental studies in biology, including integrative "omics" studies, that provide mechanistic insightsNovel experimental and computational technologiesProteogenomic data integration and analysis that enable greater understanding of physiology and disease processesPathway and network analyses of signaling that focus on the roles of post-translational modificationsStudies of proteome dynamics and quality controls, and their roles in diseaseStudies of evolutionary processes effecting proteome dynamics, quality and regulationChemical proteomics, including mechanisms of drug actionProteomics of the immune system and antigen presentation/recognitionMicrobiome proteomics, host-microbe and host-pathogen interactions, and their roles in health and diseaseClinical and translational studies of human diseasesMetabolomics to understand functional connections between genes, proteins and phenotypes

使命宣言MCP的使命是促進(jìn)蛋白質(zhì)組學(xué)在基礎(chǔ)研究和轉(zhuǎn)化研究中的發(fā)展和應(yīng)用。MCP將出版手稿，報(bào)告重要的新的生物學(xué)或臨床發(fā)現(xiàn)，以蛋白質(zhì)組學(xué)觀察為基礎(chǔ)，跨越所有的生命王國。原稿必須明確所研究的蛋白質(zhì)所起的生物學(xué)作用或它們的作用機(jī)制。該雜志還強(qiáng)調(diào)，文章描述了創(chuàng)新的新的計(jì)算方法和技術(shù)進(jìn)步，將使未來的發(fā)現(xiàn)。描述這類方法的手稿不必包含解決生物學(xué)問題的方案，但必須證明該技術(shù)如描述的那樣工作，是可復(fù)制的，并且適合使用相關(guān)的模型系統(tǒng)或公開可用的數(shù)據(jù)來揭示未知的蛋白質(zhì)/蛋白質(zhì)組功能或特性。期刊范圍生物學(xué)的基礎(chǔ)研究，包括綜合的“組學(xué)”研究，提供了機(jī)械的見解新穎的實(shí)驗(yàn)和計(jì)算技術(shù)蛋白質(zhì)基因組數(shù)據(jù)的整合和分析，使更多地了解生理學(xué)和疾病的過程信號通路和網(wǎng)絡(luò)分析的重點(diǎn)是翻譯后修飾的作用蛋白質(zhì)組動力學(xué)和質(zhì)量控制的研究及其在疾病中的作用影響蛋白質(zhì)組動力學(xué)、質(zhì)量和調(diào)控的進(jìn)化過程的研究化學(xué)蛋白質(zhì)組學(xué)，包括藥物作用機(jī)制免疫系統(tǒng)的蛋白質(zhì)組學(xué)和抗原表達(dá)/識別微生物組蛋白組學(xué)、宿主-微生物和宿主-病原體相互作用及其在健康和疾病中的作用人類疾病的臨床和轉(zhuǎn)化研究代謝組學(xué)研究基因、蛋白質(zhì)和表型之間的功能聯(lián)系